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Humoral immunity involves autoreactive B cells and plasma cells that produce high-affinity antibodies against Tg and TPO, furthering tissue injury through complement activation and antibody-dependent cell-mediated cytotoxicity (ADCC)

Glutathione is an extremely powerful antioxidant that prevents cell damage due to oxidative stress, supports skin and liver health and maintains the activity of Vitamin C and E

A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity

In addition, the numbers of patients per test group were small enough that even robust differences may have been missed, according to a chi square power analysis of proportions performed by the authors of this review