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However, if you experience significant GI symptoms throughout your entire cycle (not just around your period), or if symptoms are severe and disruptive, irritable bowel syndrome (IBS) is worth ruling out IBS symptoms often worsen around menstruation

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doi: 10.1016/j.endonu.2011.05.001 70 TuX.DuanC.LinB.LiK.GaoJ.YanH.et al

However, no significant change of p-JNK and p-p38 protein level was observed in BPC-157-treated HUVECs

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