However, the exact antiarrhythmic mechanism of flecainide remains a topic of debate and may involve a combination of sodium channel block (preventing triggered activity), inhibition of RyR2 (reducing the likelihood of spontaneous SR calcium-release events), or indirect effects on intracellular calcium handling due to changes in intracellular sodium [67, 68]
Adverse reactions following intramuscular (IM) injection have included anxiety, mild transient diarrhea, ataxia, nervousness, pruritus, transitory exanthema, and a feeling of swelling of the entire body
I also dislocated my shoulder this year 2021 and the Stem Cell treatment with a follow up PRP on that shoulder made it feel better than the arm that had no damage
Ikonen, E
For the treatment of PMS, the usual dose is 40-500mg IM/IV, given once a day
Experimenting with dosing frequency allows optimization of metabolic effects while minimizing total daily dose