semaglutide The SURPASS-2 clinical trial compared tirzeparide to semaglutide head to head
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This confirms that retatrutide's weight-loss trajectory had not plateaued at 80 weeks, unlike semaglutide and tirzepatide trials where the curve flattens between weeks 60 and 72
Additional tests such as B12/folate, CRP/ESR, liver and renal function, coeliac screen, zinc, or vitamin D may be considered based on clinical history and examination findings, rather than routinely
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Researchers should use one compound at a time