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Adverse events were rare in low doses, and higher as dose climbed

The discussion concludes with a sober look at what would need to change for peptides to become broadly usable therapies, where legitimate peptide therapeutics may expand next, and which areas of medicine stand to benefit most right now

Clinical trials show that patients on semaglutide lose approximately 3 to 4 times more weight than those on diet and exercise alone over a 12-month period

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doi: 10.1007/s00535-018-1435-5 75 GagginiMCarliFRossoCBuzzigoliEMariettiMDella LattaVet al