182 More studies further describe how aldosteronedeficient mice displayed enhanced insulin secretion without altered insulin sensitivity, and how aldosterone impairs GSIS in isolated islets
GLP-1 medications in the context of Hashimoto disease require careful thyroid monitoring, because the metabolic effects of suboptimal thyroid function can completely neutralize the caloric deficit that GLP-1 therapy creates
Unlike prior studies of AMD development that were limited to patients with diabetes, the authors wrote in their paper, their findings suggest that GLP-1 drugs "may be associated with reduced risk even in individuals with obesity but not diabetes, potentially supporting a protective benefit independent of glycemic control and mitigating diabetes as a confounding factor.
PMC 3745358
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Andy Hsieh, a biotech analyst at the investment bank William Blair, says his initial reaction upon seeing Novo Nordisks findings was, Oh man
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