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This damage can result in mutations within oncogenes such as RAS and MYC, as well as tumor suppressor genes like p53 and PTEN, thereby fostering genomic instability and malignant transformation [31, 32]

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It enables the production of high-purity, solvent-free extracts and allows precise control over extraction selectivity through pressure and temperature adjustments

An effective treatment option to prevent or mitigate the progression of renal fibrosis is IN-1130, an ALK5 inhibitor (8, 213)