The result is a vial that looks fine but contains less active peptide than you think
Groups at higher risk of deficiency include older adults (due to reduced stomach acid production), people following vegan or strict vegetarian diets (as B12 is naturally found almost exclusively in animal products), individuals with pernicious anaemia or other malabsorption conditions, those taking certain medications such as metformin or proton pump inhibitors long-term, and people with significant nitrous oxide exposure (including recreational use), which can inactivate B12 in the body
The dose and duration of injection will be decided by your doctor depending upon your health condition
It simplifies reconstitution math, prevents dosing errors, and gives you confidence that you are measuring correctly
Department of Health and Human Services
Administered by our medical professionals, B12 injections are typically well tolerated