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Correlations between the white adipose tissue metabolome and the microbiome strongly suggested that cecal Parasutterella abundance is linked to the metabolic effects of 5-Amino-1MQ treatment

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Therefore, unlike the adenovirus, lentivirus, and other AAV serotypes, the AAV9 vector is able to effectively avoid two main issues: the need for invasive injection, and compromising the integrity of the BBB, although its transduction efficiency diminishes with increasing age [156]

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