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The recent pandemic has also contributed to social isolation and the popularization of the sedentary lifestyle

mechanisms discussed in the article include copper binding, extracellular matrix signaling, fibroblast activity, collagen-related pathways, matrix metalloproteinase regulation, glycosaminoglycan synthesis, and inflammation-related pathways

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Less common but serious: pancreatitis, gallbladder disease, kidney injury, hypoglycemia (with other diabetes meds), diabetic retinopathy progression, and rare allergic reactions

LL: visualization

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