Mechanism Avg % weight loss (placebo subtracted) Dosing Side effects Cost Semaglutide GLP-1 receptor agonist : (increases insulin secretion, suppresses appetite, enhances satiety, slows gastric emptying) STEP 1 14.9% (68 weeks) STEP 5 (120 weeks): -16.5% ~1517% average sustained loss 20% loss in ~17% of users 2.4mg weekly Nausea (44%) Diarrhea (30%) Vomiting (24%) Constipation (23%) Headache, fatigue Varies widely but generally the cheaper of the two
At Touch of Tox Aesthetics, we do things differently
only 5 subjects were enrolled, despite the original plan to include 20
Several studies have also demonstrated that, unlike TRE which decreases lean mass, treatment with tirzepatide, liraglutide or semaglutide reduces body weight with small effects on lean mass (61, 64, 65)
Providers review your medical history, current medications, and eligibility before making any treatment recommendation
Beyond-use dates and expiration dates differ considerably though in terms of the quality of information they provide, so its helpful to understand the differences between them
