[ [PMID: 32152478] et al
[DOI] [PubMed] [Google Scholar] Heller-Stilb B, van Roeyen C, Rascher K, Hartwig HG, Huth A, Seeliger MW, et al
found that SIRT2, rather than SIRT1, regulates the acetylation levels and activities of glycolytic enzymes (ALDOA, PGK1, ENO1, and GAPDH), highlighting the crucial role of SIRT2 in the glycolytic pathway
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Briefly, the studies were purely observational and designed without a comparator arm