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(2018) 169:e1848

Adverse outcomes include severe developmental abnormalities and embryo-fetal death

4 Single-dose prefilled pens Lilly NDC 0002-0152-04 Zepbound (tirzepatide) injection 2.5 mg/0.5 mL Rx Only For Subcutaneous Use Needles and Syringes are not included Dispense enclosed Medication Guide to each patient

It is derived via post-translational processing of proglucagon and is secreted primarily by intestinal enteroendocrine L-cells in the small intestine and colon upon nutrient exposure, as well as by neurons within the nucleus of the solitary tract in the brainstem

Each describes laboratory or preclinical findings and is attributed to the cited study, not to this product

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