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It is also contraindicated in patients with certain kidney disorders where high-dose vitamin C is not advisable

Simon et al., 2015

[8] The researchers reported that it stimulates insulin release through the calcium channel and the adrenergic receptor pathways. Interestingly, it appears to mediate an immediate short-term response, causing a rapid GH release

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Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models

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