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The low urea level, obtained at the end of 10 d of this study, is consistent with the findings of Severin et al

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AMPK and the endocrine control of metabolism

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The use of claim 28 wherein the peptide Ac-Nle-cycVo(-Asp-His-D-Phe-Arg-Trp-Lys)- OH is employed for manufacture of a medicament for treatment by nasal administration and the PDE-5 inhibitor is employed for manufacture of a medicament for treatment by oral administration

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