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Flow cytometry-based examination of the ferrous iron levels in 5-FU-derived persister tumors revealed increased ferrous iron staining in these residual tumors ( Figure 5D )

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It is synthesized in keratinocytes and is highly upregulated in psoriatic skin [94] and epithelial skin tumors [95]

15 Treatment with antioxidants has been shown to improve vascular function and reduce blood pressure in animal models 98, 99 and in human hypertension