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This is a large, carefully designed observational study not a randomised trial so it points to a promising signal rather than a proven benefit

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According to Ro's official website, the platform lists cash-pay Wegovy pricing beginning at $199 per month for certain starter doses during a limited promotional period

Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, Maggioni AP, Marso SP, hman P, Pagidipati NJ, Poulter N, Ramachandran A, Zinman B, Hernandez AF, EXSCEL Study Group

Liselotte van Bloemendaal's 2014 imaging work showed that GLP-1 receptor activation specifically attenuates the reward system's response to food cues, the neurobiological basis of what patients call the quieting of "food noise" (van Bloemendaal et al., 2014)