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doi: 10.1016/j.numecd.2020.05.030 54 KuriyamaS

Phase 2 trial data (Jastreboff et al., NEJM, 2023) demonstrated substantial weight reduction participants lost a mean of approximately 24% of body weight over 48 weeks at the highest doses alongside improvements in cardiometabolic markers

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0.25mg or 0.5mg), it may not be enough to continue weight loss