The clinical evidence consistently shows that tirzepatide produces greater weight loss than semaglutide, and for patients who need to lose 20% or more of their body weight to reach a healthy range, that additional efficacy can be clinically meaningful
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Examples include various types of arthritis, such as osteoarthritis or rheumatoid arthritis
Although there are currently no FDA-approved oral GLP-1 medications for weight loss, early data from clinical trials hint that a pill form could be as effective as its injectable counterparts
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Patients on GLP-1 drugs may benefit from fiber supplements for digestive regularity, probiotics for gut health, and B12 supplementation to prevent deficiency that can occur with reduced food intake