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Because of its free sulfhydryl group, NAC functions as a mucolytic agent by decreasing sulfide bonds in the cross-linked glycoprotein matrix of mucus

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Conversely, T4 and BMP4 overexpression in hepatocytes can upregulate GPX4 expression, thereby inhibiting ferroptosis, reducing hepatic oxidative stress and lipid peroxidation, and providing protection against NAFLD/NASH [200, 201]