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The findings deliver early evidence that semaglutide may offer a dual benefit, targeting obesity and key reproductive challenges associated with the condition, including irregular menstruation and impaired fertility. Clare Thompson, MBBS, BSc, nMRCGP Separately, a review of five randomized controlled trials presented at ENDO 2026 found that GLP-1 drugs, such as semaglutide and liraglutide, do not appear to harm male fertility and may even improve testosterone levels and sperm quality in some men with obesity

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The harder challenge for patients, doctors, and health systems is keeping it off and sustaining the broader health gains that come with it

A systematic evaluation of effect of adherence patterns on the sample size and power of a clinical study

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CVD, the predominant cause of mortality in T2D, requires therapeutic strategies extending beyond glucose control