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The lower absolute weight loss compared to STEP 1 reflects the physiological challenges of weight management in the context of insulin resistance and diabetes medications

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Akkermansia muciniphila protects intestinal mucosa from damage caused by S

They may not be as effective for maximum weight loss as initial therapy but could be excellent for weight-loss maintenance, which is a different and arguably much more important destination for lasting health benefits, Dr

doi: 10.1038/srep19188 (2016)

It most often affects people who have diabetes