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Semaglutide as a molecule was originally developed for type 2 diabetes

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Recordkeeping: Log the daily dose, injection site and any observations to keep the protocol consistent

doi: 10.1371/journal.pone.0196579

Tirzepatide becomes the preferred choice when patients experience plateaus on semaglutide, seek maximum weight reduction potential, or carry genetic markers favoring dual-pathway activation (particularly elevated GIPR or FTO variants)

Exercise and training Resistance training is non-negotiable with either compound if you care about body composition rather than just the number on the scale