To view a copy of this licence, visit About this article Cite this article Gatta, M., Dovizio, M., Milillo, C
Winners will be biotechs and products that deliver: Systemic metabolic platforms Therapies combining fat loss with muscle preservation Long-term maintenance and relapse-prevention solutions Adherence, formulation, and delivery innovations Losers will be biotechs or products characterized by: Mono-organ, late-stage interventions Products without meaningful weight or metabolic impact Incremental add-ons justified by biomarker shifts alone Startups at Strategic Risk in the Post-GLP-1++ Era Retatrutide does not merely compete with other drugs it raises the minimum threshold of relevance
Acknowledgements The authors would like to acknowledge the facilities provided by the Department of Botany (CAS Phase VII), University of Calcutta, DBT-IPLS facility, University of Calcutta for confocal microscopy facility and IM would like to thank UGC under Government of India for CSIR-UGC NET fellowship scheme
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