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Tranexamic acid interferes with the melanocyte-keratinocyte interaction instead, which makes it gentler but less potent, and better suited to sensitive skin and milder pigmentation

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IV treatments typically show faster results than oral supplements

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Careful attention to fluid intake is important, especially during the first weeks of treatment and during dose escalation

Studies on dose optimization suggest that many patients can maintain therapeutic benefits with lower doses once theyve achieved their initial goals