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The Phase 2 trial followed participants through 48 weeks of treatment but did not include an extended washout observation period comparable to longer post-trial data available for Semaglutide
Frias JP, Choi J, Rosenstock J, Popescu L, Niemoeller E, Muehlen-Bartmer I, et al
GLP-1 medications may cause serious side effects
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found that intrathecal exenatide effectively and reversibly blocked bone cancer-induced mechanical allodynia in ipsilateral paws, with the peak effect at 0.5 h and a duration longer than 4 h in rat models of bone cancer pain [24]