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99358/99359 Prolonged services without direct patient contact (e.g., extensive chart review or family conferences)

Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007

Standard weight loss peptides can sometimes cause a disproportionate loss of lean muscle mass if patients are not consuming adequate protein or engaging in resistance training

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