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It is recognised as one of the first growth hormone-releasing peptide receptor agonists designed with high selectivity for growth hormone stimulation

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Kushner RF, et al

Individual factorsincluding body composition, liver and kidney function, concurrent medications, and genetic predispositions affecting peptide metabolisminfluence how your system processes GLP-1 compounds

Some patients experience faster eGFR decline or acute kidney injury events during GLP-1 use, usually linked to inadequate fluid intake, concurrent illness, or unrecognized baseline kidney disease