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J Med Chem 1994

[31] In the eighth step, xylulose 5-phosphate once again acts as the donor, but this time the acceptor is erythrose 4-phosphate

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also used this approach using exosomes, enabling effective prodrug conversion and tumor cell death in breast cancer and inducing tumor cell death by converting prodrug 5-FC to 5-FU in glioma, respectively [156, 157]