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The D-Retro-Inverso modification uses D-amino acids in reverse sequence, ensuring resistance to proteolytic degradation while preserving the capacity to interfere with the target protein interactions

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It is also known as CJC-1295 without DAC (Drug Affinity Complex)

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Compounds such as 5-Amino-1MQ have been developed to explore enzyme-related pathways and metabolic signalling systems in controlled laboratory environments