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It is often caused by repetitive motions, prolonged pressure on a joint, injury, or infection

In the case of GSTs, the enzymes are dimeric, with each monomer equipped with a catalytic domain

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When a person with celiac disease eats gluten-containing products, their immune system responds abnormally, causing damage to the tiny, finger-like projections that line the small intestine (villi), which play a crucial role in absorbing nutrients

10.1182/blood-2015-06-654194 20 CannavoS

The lactylation of these enzymes regulates cellular metabolism by modulating enzymatic activity, notably through feedback mechanisms that regulate glycolytic flux (108,112)