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Description

To improve the stability, bioactivity, and pharmacokinetics of GLP-1 analogues, SPPS also supports the addition of non-natural amino acids, PEGylation, lipidation, and other chemical modifications

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Step 2 Selection The 210 records were analyzed by title and abstract, resulting in the exclusion of 178 studies that did not meet the inclusion criteria because they did not address tirzepatide, had inadequate methodology, or lacked relevant clinical data

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Most patients notice changes within 6-8 weeks, though some effects (like skin tightening or body composition changes) take longer

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