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Existing and potential therapeutic uses for N -acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits

For example, a medication might strongly activate brain GLP-1 receptors for appetite suppression while only partially activating gut receptors that contribute to nausea

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FEBS Lett 382:213217 Dixon DP, Hawkins T, Hussey PJ, Edwards R (2009) Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily

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GLP-1 medications cost $650 to $1,300 per month without insurance