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It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)

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A series of reactions take place and move electrons across the inner membrane of the mitochondria

The net result

Patients who stay on treatment through six months nearly double their weight loss, and maximum benefits appear around the one-year mark

Activated and functional autophagy is linked with life longevity (Cant and Auwerx 2009)