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However, the organization recently declared that the shortage has been resolved and compounding is no longer permitted

Most patients report decreased hunger and earlier satiety within the first one to two weeks of starting GLP-1 therapy

For women with PCOS or obesity-related menstrual irregularities, weight loss from GLP-1 medications may actually restore regular ovulatory cycles

Long term safety concerns Long term use of GLP-1RA may increase the risk of medullary thyroid cancer (MTC), as well as gastrointestinal side effects (such as nausea, vomiting, diarrhea) and the risk of acute pancreatitis

Severe events are rare, and treatment discontinuation due to side effects is uncommon

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