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UPLC-TOF MS analysis of methanolic or ethanolic solutions containing the synthesized dipeptides D- O -Leu-D-Ala and L- O -Val-L-Val, or purified cereulide did not reveal even trace amounts of the candidate peptide methyl or ethyl esters after incubation for 4 days at room temperature (data not shown)

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SIRT1 activators such as salidroside, ulinastatin, rosa rugosa and dihydroquercetin, have been shown to significantly improve liver pathological changes associated with ferroptosis by reducing oxidative stress and inflammatory responses (Wang et al., 2021