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Furthermore, lower levels of UA are significantly related to impairments in tests that asses executive function, verbal memory, cognitive flexibility, non-verbal intelligence, and language [134, 135]
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Kirkman HN et al
In addition, factors affecting oxidative stress, the necessary co-factor in APAP-induced neurological injury (discussed in detail below), may change over time [41]
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Also, both systolic and diastolic dysfunction stemming from the interplay between atherosclerotic coronary disease and diabetic cardiomyopathy are associated with the underlying pathophysiology of HF in patients with T2DM [45, 46]
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