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Cracked corners of the mouth Vitamin B deficiencies, especially vitamins B2 and B3, have been linked to cracked corners of the mouth and other symptoms such as dry skin, a red tongue, and a swollen mouth

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In addition, the availability of novel cellular systems, such as cybrids or induced pluripotent stem cells, offers the chance to exploit the advantages of an in vitro investigation, although mirroring more closely the cell population being affected (Wang et al

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