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Blood analyses will be performed in plasma or serum as required and under standard conditions

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Tumors in this group are characterized by biallelic inactivation of the tumor suppressor gene BAP1, mostly through association with a truncating mutation in one of the alleles of chromosome 3 (locus 3p21) and complete or partial loss of the other

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47 As a result, microneedle technology has begun to attract the attention of researchers, who are trying to use this technology to achieve high-efficiency transdermal delivery of these difficult-to-deliver drugs