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conducted prospective and retrospective observational studies on the efficacy of the combination of duloxetine (DLX) and pregabalin (PGB) for the treatment of FM syndrome, and the possibility of additional benefits with the addition of the lipid signaling molecule palmitoylethanolamide (PEA) [59]

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150mg alpha lipoic acid a key nutrient within cells, that biologically regenerates other nutrients, specifically glutathione, vitamins C and E, and coenzyme Q10

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There is strong evidence that 100-300 mg per day of COQ10 supplementation can help, and D-ribose may be beneficial as well