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doi: 10.1016/j.heliyon.2024.e29695 468 EkawardhaniSBerbudiA

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Some CB1 antagonists, such as rimonabant, have been investigated in clinical trials for obesity, metabolic diseases, and drug abuse

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And Dr Aiken is right that there's no reason to neglect methylfolate in the context of some autisms, particularly where 'issues' with a certain gene - MTHFR - may also be present