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Case 2: Due to a national shortage of 1.0 mg semaglutide, a female whose weight was previously stable on phentermine 15mg/topiramate 25mg twice daily plus GLP-1 agonist therapy (i.e., semaglutide) was switched to 5mg tirzepatide in-between clinic visits

It was FDA approved in 2023 and has shown impressive results so far

You can take semaglutide orally as a tablet you swallow

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Tirzepatide delays gastric emptying, and Zepbound trials reported belching in 4% to 5% of dose groups versus 1% with placebo

As a physician, Ive seen a growing need for a more personalized, gentler approach: microdosing