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83 Interestingly, AIH was also obviously reduced in mice with 5-lipoxygenase (5-LO) deletion, which was related to the inhibition of cytochrome P450 3A11 (CYP3A11)

Transcriptome GO enrichment analysis comparing DEGs from the Gly and NC groups in mice showed that the Fatty acid metabolic process, Lipid catabolic process, Lipid transporter activity, Fatty acid transmembrane transporter activity, were enriched and downregulated significantly (Fig

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1c-f), to maintain its low expression