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Andrews CN, Bharucha AE, Camilleri M, Low PA, Seide BM, Burton DD, et al

Distinguishing cardiac from noncardiac causes is important because of the risk of sudden death in those with an underlying cardiac etiology

Patient adherence may theoretically improve with patch-based delivery, as some individuals find regular injections burdensome or anxiety-provoking

In the SURPASS clinical trial program for type 2 diabetes, patients achieved HbA1c reductions of 1.9% to 2.6% depending on dose, with weight loss averaging 15-22 pounds across studies

Therefore, an effective treatment would be expected to augment synaptic connectivity, protect neurons from underlying death inducers, and stimulate the replacement of lost neurons from preexisting pools of neural stem cells

While absorption characteristics differ, many patients achieve comparable weight loss results with the added convenience of needle-free daily administration