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Paying attention to how different foods make you feel can help refine choices

The decision

It was originally used, and still is, to treat type 2 diabetes by regulating blood sugar levels

The main concern is stacked GI side effects - both compounds slow digestion through different pathways, so combining them can amplify nausea, vomiting, and constipation

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GLP-1 only treatments and oral options still deliver strong results but typically show slightly lower average weight loss because they target a single receptor pathway