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This builds on his work to understand 'how circulating GLP-1 can produce multiple actions, both directly and indirectly, on multiple organs' which he has pursued for many years with colleagues (McLean, Wong, Campbell)

The increase in genital mycotic infections is due to the glycosuria as glucose is an excellent substrate for the growth of Candida

Weeks 1-4: light activity like walking 20-30 minutes daily

These side effects may be more pronounced when starting treatment and often decrease over time

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Their main function is to stimulate insulin secretion from pancreatic beta cells, but they also regulate metabolism in other ways