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Prescription drugs are the third leading cause of death after heart disease and cancer in the United States and Europe

As illustrated in Figure 2 , these substances or antigenic compounds traverse the gut-liver axis, stimulating macrophages and LCMs within the hepatic portal region, which then initiate either pro-inflammatory or anti-inflammatory immune responses

Contaminants, endotoxins, and inaccurate dosing are real-world hazards that may cause harm independent of the peptide's own pharmacology

doi: 10.1016/0005-2736(93)90360-C 11 SweeneyJDArduiniA