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given known sex differences in metabolic and circadian physiology, whether female mice exhibit similar regulation of CI in adipose tissue is to be determined

Yes, though it requires extremely precise syringe reading

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The overall percent weight loss from baseline, ITT-LOCF analysis, showed a 9.8% weight loss for patients taking the top dose (15 mg/92 mg) of Qsymia and 7.8% for patients who took the recommended dose (7.5 mg/46 mg), compared to 1.2% in the placebo group ( P 4,500 people [43, 44]