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It binds GHS-R1a with high affinity but shows minimal activity at other receptor systems, including those mediating cortisol release (CRH/ACTH axis), prolactin release, or appetite stimulation pathways independent of GH signaling
This could be a direct pharmacological effect or a secondary response to other systemic changes the peptide is inducing
Arias EB, Zheng X, Agrawal S, Cartee GD (2019) Whole body glucoregulation and tissue-specific glucose uptake in a novel Akt substrate of 160 kDa knockout rat model
10.1159/000077996 32 JainC
JOE ROGAN: Its dependent on genetics
It works well as a skin-enhancing nutrient when used in combination with a balanced diet
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