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Glucagon-like peptide-1, or GLP-1, is a hormone naturally produced by your intestines

Lateral hypothalamic GLP-1 receptors are critical for the control of food reinforcement, ingestive behavior and body weight

The osteogenic effect of liraglutide involves enhanced mitochondrial biogenesis in osteoblasts

5 For example, recent preclinical and clinical observations highlight the role of gut-derived peptides such as GIP, GLP-2, and to a lesser extent, GLP-1 in the maintenance of overall skeletal health ( Figure 2 ), 6,7,8 opening new avenues for the understanding and potential treatment of bone disorders

Miki, T

PMID 25493285